10-hydroxycamptothecin
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| Product Status : | New |
| Sample Available : | yes |
| Shipment Terms : | fob,cfr,cif,Negotiable |
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Description
10-hydroxycamptothecin CAS No.: 19685-09-7, 7689-03-4 Appearance: Light Yellow Crystal Powder Solubility: Insoluble in water, its sodium salt is the water-soluble, its organic solution has blue fluorescence. Specification: 10-hydroxycamptothecin >98% Functions: 10-hydroxycamptothecin is the derivative of camptothecine that is a micro-alkaloid from camptotheca Acuminate (a tree native to mainland China). Is a kind of pharmaceutical intermediate, an alkaloid originally isolated from the Camptotheca acuminata, exerted inhibitory effects on DNA topoisomerase (Topo )[1]and has anticancer activity in vitro and in vivo. It can also induce differentiation of leukemia MELC[2]and HL-60[3]cells. The purpose of this study is to investigate the proliferation-inhibiting and differentiation-inducing actions of HCPT on human hepatoma Hep G2 cells.
