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vilazodone intermediate

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  • vilazodone intermediate

Product Property

Product Status : New
Sample Available : yes
Shipment Terms : fob,cfr,cif
Payment Mode : T/T,PayPal,Negotiable

Description

Name:vilazodone intermediate
CAS: 143612-79-7; 163521-20-8;183288-46-2;765935-67-9
Useage: Vilazodone Intermediates

Vilazodone acts as a serotonin reuptake inhibitor (IC50 = 0.5 nM) and 5-HT1A receptor partial agonist (IC50 = 0.2 nM; IA = ~60-70%).[6][7] It has negligible affinity for other serotonin receptors such as 5-HT1D, 5-HT2A, and 5-HT2C.

Partial agonism of the 5-HT1A receptor is a relatively novel mechanism of action and is also shared by the anxiolytic buspirone (Buspar), and the atypical antipsychotic / antidepressant aripiprazole (Abilify).


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