- Organic Chemicals
- Hormones, Prostaglandins, Thromboxanes And Leukotrienes, Natural Or Reproduced By Synthesis; Derivatives And Structural Analogues Thereof, Including Chain Modified Polypeptides, Used Primarily As Hormones.
- Somatropin, Its Derivatives And Structural Analogues, Used Primarily As Hormones
vilazodone intermediate
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Product Status : | New |
Sample Available : | yes |
Shipment Terms : | fob,cfr,cif |
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Description
Name:vilazodone intermediate
CAS: 143612-79-7; 163521-20-8;183288-46-2;765935-67-9
Useage: Vilazodone Intermediates
Vilazodone acts as a serotonin reuptake inhibitor (IC50 = 0.5 nM) and 5-HT1A receptor partial agonist (IC50 = 0.2 nM; IA = ~60-70%).[6][7] It has negligible affinity for other serotonin receptors such as 5-HT1D, 5-HT2A, and 5-HT2C.
Partial agonism of the 5-HT1A receptor is a relatively novel mechanism of action and is also shared by the anxiolytic buspirone (Buspar), and the atypical antipsychotic / antidepressant aripiprazole (Abilify).